Misuse of testosterone can cause dangerous or irreversible effects. Testosterone injections should only be administered by a healthcare professional. Testosterone can cause serious problems with the heart, brain, liver, and endocrine and mental health systems. Stopping taking testosterone can also cause unpleasant withdrawal symptoms. Misuse can cause serious side effects or death.
Misuse of testosterone can cause dangerous or irreversible effects, such as breast enlargement, small testicles, infertility, high blood pressure, heart attack, stroke, liver disease, bone growth problems, addiction, and mental effects such as aggression and violence. Adequate testosterone treatment can restore venous loss in the corpus cavernosum, which is a common etiologic factor of erectile dysfunction in older men. Serum testosterone varies during the day and levels peak between 08:00 and 10:00 hours; a serum sample must be obtained between 07.00 and 11.00 a.m. At the same time, many studies271 to 273 have not demonstrated a significant exacerbation of urination symptoms attributable to benign prostatic hyperplasia during testosterone supplementation, and there have been no complications such as urinary retention at higher rates than in placebo-receiving controls, nor was there any difference in urine flow rates, post-mictional residual urine volumes, and symptoms of prostatic urination with patients who received treatment in these studies.
Seek emergency medical attention if you have any signs of a blood clot in your lung after using testosterone. Hypogonadal patients with a history of prostate cancer had no PSA recurrence for a median of 19 months and showed statistically significant improvements in total testosterone and hypogonadal symptoms. This medication is only approved for use in men who have low levels of testosterone related to certain medical conditions.
Benign and malignant liver tumors, intrahepatic cholestasis, hepatotoxicity, and liver failure have been reported with testosterone replacement therapy.
The benefits and risks of testosterone treatment should be clearly discussed with the patient and prostate and other risk factors evaluated before starting treatment with testosterone.In patients receiving oral testosterone tablets, the serum level should be measured immediately before the application of a new system. Transient decreases in serum testosterone levels, such as those due to acute illnesses, should be excluded by careful clinical evaluations and repeated hormone measurements. These fluctuations in testosterone levels can cause variations in libido, sexual function, energy, and mood.
